with concurrent pulmonary manifestations and later disability. Aim of Work:\nTo evaluate the level of exhaled fraction of nitric oxide (FENO) and fraction\nof exhaled carbon monoxide (FECO) as markers of pulmonary tuberculosis\nTB activity in patients under chemotherapy in comparison to healthy negative\npatients and latent TB patients. Patients and Methods: This cross-sectional\nstudy was conducted on 130 patients recruited from the outpatient clinic of\nMansoura Chest hospital during the period from May 2019 to December 2019.\nThey were categorized into the three groups: 1) Pulmonary tuberculous patients\nPTB (group1) which included 48 cases with positive sputum for TB\nbacilli in the initiation phase after 1 month of starting anti-tuberculous chemotherapy;\n2) Latent patients (group 2): included 40 patients with positive tuberculin\nskin test (Mantoux test) > 10 mm. 3) Control patients (group 3)\nwhich included 42 healthy volunteers with negative sputum for TB bacilli.\nThey were subjected to portable spirogram as well as exhaled fractional NO\nand CO measurement. Results: FECO and FENO levels prevailed in pulmonary\nTB patients followed by Latent TB patients and lastly healthy volunteers..................
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